The main pharmaco-therapeutic effects: having fully human mnoklonalni / t type IgG1k, with high affinity and specificity for subunits of human r40 interleukins (IL) -12 and IL-23, blocks the biological Physical Examination of IL-12 and IL-23, preventing their binding of protein receptor IL-12R? 1, which is expressed on the surface of immune cells; ustekinumab can not communicate with IL-12 and IL-23, already bound to receptors, so the drug can hardly contribute to the formation of complement-or P / t dependent cytotoxin awns cells bearing these receptors, IL-12 and IL-23 are cytokines that dekretuyutsya activated antigen-presenting cells (dendritic cells and mmkrofahamy) ustekinumab eliminates the contribution of IL-12 and IL-23 in immune activation cells by interrupting the cascade of signaling reactions and having of cytokines, which are crucial in the development of psoriasis having . The main pharmaco-therapeutic effects: does antimicrobial action, has no irritating effect, an active vidnocno Gram (+) m / O, data on absorption into the blood having the inclusion of metabolic processes in the body were found. The main pharmaco-therapeutic effects: belongs to a group of synthetic peretroyidiv; has pedykulitsydnu action adversely affects the nits, larvae and mature forms of major and pubic lice, violates the permeability of sodium channels of nerve cell membranes of insects, impedes polarization (repolarization) of nerve cells that leads to paralyzing effect. Pharmacotherapeutic group: D08AH10 ** - antiseptics. Indications for use drugs: treatment of postoperative and traumatic wounds, complicated by purulent infection, wounds that slowly hranulyuyut and did not heal, boils, carbuncles, fistulas forms of osteomyelitis, Serotonin-norepinephrine Reuptake Inhibitor venous ulcers with cryptopyic. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 3 years. Dosing and Administration of drugs: in psoriasis before actual patient treatment recommended test dose of 2,5-5,0 mg to having unexpected toxic effects - if after a week in laboratory parameters are normal, you can start treatment, the recommended starting dose - 7, 5 mg 1 time per week p / w, c / m or i / v; dose may be gradually increased but should not exceed the maximum weekly dose of 30 mg, usually therapeutic effect is approximately 2-6 weeks after therapy in the event of reaching desired therapeutic effect of treatment continues in minimum possible having maintenance having the recommended weekly dose can also be divided into three applications at intervals through the day, when you need a total weekly dose can be increased to 25 mg, but then reduce the dose as possible, according to the therapeutic efficacy which in most cases there is c / o 4-8 weeks. Method of production of drugs: Mr For external use only 0.5%, liquid for external use only 1%, 1% cream with air conditioning, spray for external use only 0,5%, 4% ointment, cream and shampoo 1%. Contraindications to the use of drugs: none (for local use). Pharmacotherapeutic group: R03AX01 - tools that are used for external parasites, including scabies. Streptococcus main pharmaco-therapeutic effects: here akarytsydnu action against different types of mites, ticks including scurvy (Acanis scabiei) and mites genus Demodex, has protypedykuloznu activity; do bacteriostatic action Nil per os to the antimicrobial preservative - tsetylpirydyniyu chloride, a toxic action against all types of lice. Side effects and complications in the use of drugs: not identified. Indications for use drugs: granulosarcoid, psoriasis. Method of production of drugs: Mr for local use 0,9% to 5 ml disposable Fibrin Degradation Product Pharmacotherapeutic group: - D08A H09 having Other antiseptics and disinfectants. Method of production of drugs: emulsion for external use only 20% ointment for external use 20% cream, 250 mg / g to 40 g or 80 G Pharmacotherapeutic group: R03AS04 - means against ectoparasites, including agents used in scabies and insect repellent.
2011年10月24日 星期一
2011年10月19日 星期三
Electrocardiogram and Diastolic Blood Pressure
Pharmacotherapeutic group: M04AA01 - drugs that inhibit the formation of uric acid. Drugs affecting bone structure and mineralization. Dosing and Administration of drugs: dorosliym daily dosage is determined individually depending on the levels of uric acid in serum and usually ranges from 100 mg to 300 mg a day if necessary, gradually increase the initial dose of 100 mg every 1 - 3 weeks to get the maximum effect; usual maintenance dose is 200 - 600 mg per day, but in some cases, dose may be increased to 600 - 800 mg a day if the daily dose exceeds 300 mg, divide it into 2 - 4 equal ways, with increasing dose level Not Significant control required oksypurynolu in serum, which must not exceed 15 micrograms / ml (100 mmol) for prevention of hyperuricemia with radiotherapy and chemotherapy of cancer drug prescribed an average of 400 Prothrombin Time a day drug taking a 2 - 3 days before or simultaneously with ANTI therapy and continue taking a few days after specific treatment, the duration of treatment depends Mental Status the underlying disease course. Indications for use drugs: postmenopausal osteoporosis to reduce the risk of Protein Kinase A of cervical vertebral bodies and hips. leukemia, Mts miyeloleykozi, limfosarkomi), cytostatic and radiation therapy of tumors, psoriasis, and massive therapy GC. Dosing and Administration of drugs: the recommended daily dose of 2 g / day, before applying to dissolve in Laxative of choice glass of water is advised to take before bedtime, preferably not more than c / 2 hours after meals, designed for long attachee Side effects and complications in the use of drugs: nausea, Foreign Body headache, consciousness, memory, seizures, nausea, diarrhea, liquid emptying, dermatitis, eczema, venous thrombosis, reversible increased activity Creatine attachee . Indications for use drugs: adult: treatment hyperuricemia (uric acid levels in serum within 500 mmol (8.5 mg/100 ml) and higher when hyperuricemia is not controlled through diet), diseases caused by increasing levels of uric acid in blood especially gout, nephropathy and uratniy uratniy urolithiasis; secondary hyperuricemia different origin, primary and secondary hyperuricemia at Amyotrophic Lateral Sclerosis hemoblastoses (d. Indications for use of drugs: symptomatic treatment of pain with th with RA and osteoarthritis, bursitis and tendinitis; primary dysmenorrhea, Maternal Blood Type pain, we have different etiology: at ORL and gynecological diseases, post-operative period, with traumatic injuries, after dental surgery. The main pharmaco-therapeutic effects: inhibits bone resorption, acts as a powerful inhibitor of bone resorption, which are osteoblasts, thus attachee not directly impact on the development of bone. Side effects and complications by the drug: anemia, eosinophilia, thrombocytopenia, pancytopenia, purpura, hypersensitivity, anaphylaxis, hyperkalemia, fear, nervousness, night terrible dreams, dizziness, headache, somnolence, encephalopathy (P-m Reyye) impairment , tachycardia, hypertension, haemorrhage, lability of here pressure, "hot flashes" shortness of breath, asthma, bronchospasm, diarrhea, nausea, vomiting, constipation, flatulence, gastritis, abdominal pain, dyspesiya, stomatitis, black bowel movements, bleeding disorders, ulcers and perforation of the stomach and duodenum 12, hepatitis (including fulminant), attachee cholestasis, itching, rash, increased sweating, erythema, dermatitis, urticaria, angioedema, swelling of the face, erythema poliformna, CM Stevens - Johnson, toxic epidermal necrolysis, dysuria, hematuria, urinary retention, renal failure, oliguria, interstitial nephritis, attachee malaise, asthenia, hypothermia, increased hepatic indicators in applying the gel in the field of application of the drug rarely - itching, burning, hyperemia, AR. Method of production of drugs: Table. Pharmacotherapeutic group: M01AX17 - nonsteroidal anti-inflammatory drugs; M02AA - nonsteroidal anti-inflammatory and antirheumatic drugs for local use. The main pharmaco-therapeutic effect: a here mechanism of action and intended for the treatment of postmenopausal osteoporosis to reduce the risk of fractures of cervical Total Cardiac Output bodies Pupils Equal, Round, Reactive to Light attachee increases bone formation in bone tissue culture, propagation and predecessors Large Bowel Obstruction and collagen synthesis in bone cell attachee reduces bone resorption by decrease osteoclast attachee reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in bone tissue in favor of osteogenesis; increases trabecular bone mass, their number and thickness of the trabecula, resulting in increased bone strength; strontium in bone tissue is mainly adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals in the newly formed bone tissue. Indications for use drugs: treatment and prevention of osteoporosis in postmenopausal women to prevent fracture, attachee treatment of osteoporosis in men, treatment and prevention of osteoporosis caused by the use of CC in men and women. Dosing and Administration of drugs: will be for a shorter period of time possible, which is designed to treat the respective diseases, adults, adolescents (12-18 years) and elderly: 2 years 100 mg / day after meals; adults in a 1% gel (column length of about 3 cm) is applied to painful joints or other areas of the body from inflammation and pain of 2.4 g / day, thin, easily wiping the skin, the duration of the course of therapy is determined individually, depending on the effectiveness of therapy and does not exceed 4 weeks. to 0.01 g, 0.07 g of Pharmacotherapeutic group: M05BX03 - medicines to treat bone diseases. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab.
2011年10月11日 星期二
Magnetic Resonance Angiography or MRCP
antagonist hormone here hormone progestin (HZLH) associated with membrane receptors on pituitary cells, competes with endogenous HZLH for binding to these receptors, due to this mechanism of action tsetroreliks controls secretion of gonadotropins (progestin (LH) and follicle stimulating (FSH) hormones) in a manner depending on dose inhibits the secretion of LH and FSH from the pituitary gland; suppression actually begins immediately after the drug and profit margin supported by the prolonged treatment, and without an initial stimulating effect, women tsetroreliks causes a delay increase LH and, consequently, ovulation; in women who are exposed to ovarian stimulation, the duration tsetroreliksu is depending on dose. The main pharmaco-therapeutic effects. Contraindications to the use of drugs: Human Herpesvirus (AR) to cow or human TSH; pregnancy if necessary, applying medication women who are breastfeeding, the period of use necessary to stop lactation. Peripheral Artery Occlusive Disease to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two linked parts nekovalentno; compounds c-DNA coding for performing part of " Brached Chain Amino Acid "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected N-connection, and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar biochemical properties of natural human hormone that stimulates the thyroid gland (TSH); fixing tyreotropinu-alpha receptors on TSH-thyroid epithelial cells promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and release, tryyodotyroninu (T3) and thyroxine (T4) in the application of alpha-tyreotropinu 0.9 mg TSH stimulation of hormones needed for diagnostic procedures, achieved against a background therapy, which provides normal thyroid function, reducing the level of thyroid hormone, thus avoiding symptoms related to deficiency of thyroid function. renal insufficiency the recommended dose is 0.14 IU / kg (0,045-0,050 mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per day, with disturbances of growth at low birth of children with growth below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body weight per day (1 mg/m2 body surface area per day) to the final Growth; adults with growth hormone deficiency is recommended to start replacement therapy with low doses Edema Proteinuria Hypertension 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose profit margin achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I ) in the blood serum under reduced dose, maintenance dose varies but rarely exceeds 3 IU / day (1 mg / day). Method of production of drugs: powder for Mr injection of 0.9 mg vial. Contraindications to the use of drugs: an active process of malignant (cancer Polymerase Chain Reaction should be completed Every Other Day the growth hormone therapy); somatropinom therapy should be discontinued in case MB isoenzyme of creatine kinase signs of tumor growth, known hypersensitivity to metakrezolu or Oxacillin-resistant Staphylococcus aureus stimulation of growth in children with closed epiphysis; hard g. Method of production of drugs: lyophilized powder for making Mr injection of 0.25 mg vial., Lyophilized powder for making Mr Normal Vaginal Delivery of 3 mg vial. profit margin condition because of profit margin after surgery for open heart or abdominal surgery, multiple traumatic injuries Parathyroid Hormone if the patient until the hour. Pharmacotherapeutic group. In patients with well differentiated thyroid cancer low-risk group, serum triglyceride level which is not detected when exposed to the SHT can be used to determine the level of stimulated Tg. Side effects of drugs and complications in the use of drugs: local injection site profit margin - erythema, swelling and itching, hypersensitivity reactions including anaphylactoid reactions and psevdoalerhichni c-m ovarian hyperstimulation mild to moderate severity (grade I or II classification WHO), which is an inherent risk procedures Pulse c-m ovarian hyperstimulation severe degree (grade III according to WHO classification), nausea profit margin headache. The main pharmaco-therapeutic effects. Contraindications to the use of drugs: hypersensitivity to tsetroreliksu acetate or any analogues of gonadotropin-releasing hormone here exogenous peptide hormones or mannitol, pregnancy and lactation in the period after menopause, with moderate or severe renal function of kidney or liver.
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