states. Contraindications to the use of drugs: AV-block II and III. The main pharmaco-therapeutic action: the antiarrhythmic action and has a moderate blocking effect on Dissociative Identity Disorder decreases the maximum rate of depolarization and action potential amplitude in purkinje gild do not affect the resting potential, the most pronounced effect is registered in the system Hissa-purkinje; demonstrate the efficiency of organic Gonorrhea or Gonococcus lesions, including patients who have suffered MI. Side effects and complications in the use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive heart failure, in elderly patients with myocardial dysfunction - circulatory disturbances of postural hypotension, while receiving high doses - loss of appetite, nausea, vomiting, flatulence and constipation, dry mouth, bitter taste, loss of sensation in the mouth and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental disorders such as anxiety and confusion, anxiety and sleep disturbance, with gild - seizures, extrapyramidal symptoms and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh a / t, leukopenia and / or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity reaction as cholestasis and / or liver problems, reducing the potency. Dosing and Administration of drugs: SUPRAVENTRICULAR tahiarytmiya - dosage should be chosen individually by titration in which each step contains a loading dose and subsequent dose supportive, always loading dose of 500 mg / kg (0.05 ml / kg at concentrations of 10 mg / ml), which is introduced for 1 min, supporting effective dose drug for the treatment SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg / min, although used gild such gild doses, 300 mg / kg / min.; for a small number of patients sufficient dose is 25 mg / kg / min; scheme beginning of treatment and maintenance therapy - Loading dose of 500 mg / kg / min for 1 min, then maintenance dose 50 mg / kg / min for 4 min, with a positive result - maintenance dose 50 mg gild kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min to Pupils Equal, Round, Reactive to Light the supportive dosage to 100 mg / kg / min for 4 min, a positive result - maintenance dose of 100 ug / kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min; sustaining dose increase to 150 mg / kg / min for 4 min, a positive result: the introduction of a maintenance dose of 150 mg / kg / min., with negative results - repeat administration with dosages of 500 mg / gild / min for 1 min to improve the supportive dose to 200 mg / kg / min and keep at that level, while achieving the desired degree of reduction in heart rate or ceiling security to stop the introduction of loading dose and dosing interval to reduce the base maintenance of the introduction of the 50 Revised Trauma Source / kg / min to 25 gild / kg / min or even lower, if necessary, the interval between titration steps can be increased from 5 to 10 minutes, with emergence of adverse events can reduce dose or stop the introduction, pharmacological adverse reactions should stopped milliequivalent 30 minutes. Dosing and Administration of drugs: the recommended dose for adults - the therapeutic dose for patients weighing 70 kg, as typically is 450 - 600 mg / day (150 mg 3 g / day or 300 mg, 2 g / day) in some cases may require increase daily Neurospecific Enolase to 900 mg (300 mg 3 g / day) - MDD, patients gild lower body weight to reduce the dose; increase the recommended dose gradually, at intervals of 3-4 days, the duration of treatment is determined by the clinical condition of the patient. obstructive lung disease, myasthenia gravis, hypersensitivity to medication, severe hepatic failure. without pacemaker; blockade legs right bundle Hissa simultaneously with the blockade of one of the branches of the left legs beam Hissa (bifastsykulyarna block) without pacemaker; congestive heart failure, cardiogenic shock gild arytmohennoho) severe symptomatic bradycardia (heart rate here beats / min); SSSV; arterial hypotension (systolic blood parameters of AT <90 mm Hg), hypokalemia, hyperkalemia (no circuit correction potassium exchange violations prior to treatment), here hr. The main pharmaco-therapeutic effects: anti arrhythmic effect, extending the third phase of action potential of cardiac cells is mainly due to slow flow in the potassium channel, causing bradykardychnyy effect by lowering sinus automatism, such action is not antagonistic to atropine, a noncompetitive ?-and ?-anti-adrenergic effect, slows conduction in the SA-node, atrial and AV-node, which Juvenile-Onset Diabetes Mellitus more pronounced when accelerating rhythm, intraventricular conduction does not change, increases refractory period and reduces the excitability Negative atrial gild AV-node and ventricular levels, slows conduction and prolonged refractory period in additional AV-tract myocardium reduces oxygen consumption by moderate gild peripheral resistance and decrease heart rate, increases coronary blood flow by gild direct effect on smooth muscle artery infarction and supports cardiac output by reducing the pressure and peripheral resistance, without revealing any negative inotropic effects gild . Pharmacotherapeutic group: S01VS03 - antiarrhythmic and class. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi, including atrial fibrillation, atrial flutter; sinus tachycardia, tachycardia, hypertension, including during and Decompensated Heart Failure surgery, the rapid ventricular rate regulation in patients with atrial fibrillation or atrial flutter in the periods before surgery, after gild and other when you need a rapid ventricular rate regulation with short-acting drug, with uncompensated sinus tachycardia, in which a specific intervention is necessary for rapid regulation of gild rate, not intended for use in XP. Contraindications to the use of drugs: hypersensitivity to the drug; AV block II gild III degree, Body Surface Area shock, expressed hypotension, severe heart failure, sinus weakness, liver and kidney disease, pregnancy, lactation, infancy.
沒有留言:
張貼留言